Barcelona vs Inter Milan: UEFA Champions League Semifinal Best Bets

Yesterday, Paris Saint-Germain was able to take a 1-0 aggregate lead against Arsenal on the road, will our visitors be able to do the same in the second UEFA Champions League Semifinal today? Playing in their first leg, Inter Milan travels to Spain to take on the high flying offense of Barcelona.

Both teams have played 12 matches so far in this competition, and it’s really been a tale of two different ways to get to the semifinals. For example, Barcelona has netted 37 goals in this tournament, averaging over three per match, but they are also allowing 1.41 from their opponent, given they’ve conceded 17 in their 12 matches. As for Inter Milan, they have relied heavily on defense.

Inter has only scored 19 goals in their 12 matches, however, they have only given up five total. Less than half a goal per match. And, they’ve only allowed two on the road and three at home. This backline is phenomenal, but they will certainly need it against the Barcelona attack.

Barcelona vs Inter Milan: UEFA Champions League Semifinals

Matchup Information – Barcelona vs Inter Milan

• Venue & Location: Estadi Olímpic Lluís Companys (Barcelona, Spain)
• Date: Wednesday, April 30th, 2025
• Kick Off: 3:00pm Eastern
• Broadcast: CBS/Paramount+

Betting Odds

Odds are courtesy of BetOnline, an industry leader in the sports betting world. Sign up today using code FREE250 and get a 50% deposit bonus up to $250 AND 100 Free Spins at the casino.

Money Line

• Barcelona -156
• Draw +333
• Inter Milan +412

Draw No Bet

• Barcelona -365
• Inter Milan +285

Total

• Over 3 (-108)
• Under 3 (-112)

Barcelona’s offense is insane, and Inter surely knows that. But the Spaniards have also been incredible at home. The two differing styles of play will certainly clash on the field, and if I’m Inter, I want this to go to PKs back in Italy. The Italians have the advantage of hosting the 2nd leg, meaning any extra time or penalty shootout will be at their own stadium.

Knowing this, look for Inter to play very conservative soccer for much of the entire match today. A scoreless draw on the road is a win in their book, especially going back home for a chance to advance. However, Barcelona’s attack will not be denied, not even by the current best back line in Europe (Arsenal lost that title after losing yesterday).

Barcelona vs Inter Milan Best Bets

Barcelona vs Inter Milan Prediction: Barcelona Wins 2-1 (+750)

Best Bet: Barcelona ML/Over 1.5 (-116)BetOnline

We aren’t asking for too much, at least I don’t think so. I thought long and hard about the under 3, but as you can see there’s a chance Barcelona concedes a goal despite their high flying attack. Inter always seems to find the back of the net when they most need it.

Anyways, a little parlay never hurt anybody. Barcelona has won three straight matches, all of them at home, and have actually won 8/L9 in Spain and are completely unbeaten at home in the 2025 calendar year. This team has scored at least two goals in all six matches at home in the UEFA Champions League this year, averaging 3.5 goals per match on their own turf. While Inter has a very good back line, I think “slowing down” Barcelona entails holding them to two goals tops, with the thinking of being aggressive back home next week.

Thinking out loud (READ: As I type), Barcelona and the Under 4.5 at (+105) on BetOnline could also be a play, but you always run the risk of Barcelona having “one of those games”…. you know what I mean.

Give me a Barcelona victory with at least two balls in the back of the net for reasonable juice.

Still Want More Soccer Content?

Here at Betting News, we offer Free Expert Picks for every major sports league. We also host daily streams on our Twitch Channel with our best bets, as well as sweat out games on Playback! Be sure to tune into everything we have going on at our Youtube, TikTok, and X pages as well.

• Expert Soccer Picks
• English Premier League Preview
• USMNT Hire Next Head Coach